Utility of voriconazole therapeutic drug monitoring: a meta-analysis
نویسندگان
چکیده
منابع مشابه
Voriconazole therapeutic drug monitoring.
We report on 28 patients who underwent voriconazole monitoring because of disease progression or toxicity. A relationship (P<0.025) between disease progression and drug concentration was detected. Favorable responses were observed in 10/10 patients with concentrations above 2.05 microg/ml, while disease progressed in 44% (n=18) of patients with concentrations below 2.05 microg/ml.
متن کاملVoriconazole Pharmacokinetics and Therapeutic Drug Monitoring : A Multi - Center Study
Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring: A Multi-Center Study 1 2 Michael J Dolton, John E Ray, Sharon C-A Chen, Kingsley Ng, Lisa G Pont, Andrew J 3 McLachlan 4 5 1 Faculty of Pharmacy, University of Sydney, Camperdown, Australia 6 2 Clinical Pharmacology & Toxicology, SydPath, St Vincent’s Hospital, Darlinghurst, 7 Australia 8 3 Centre for Infectious Diseases & Microbiol...
متن کاملVoriconazole Pharmacokinetics and Therapeutic Drug Monitoring : A Multi
Voriconazole Pharmacokinetics and Therapeutic Drug Monitoring: A Multi-Center Study 1 2 Michael J Dolton, John E Ray, Sharon C-A Chen, Kingsley Ng, Lisa G Pont, Andrew J 3 McLachlan 4 5 1 Faculty of Pharmacy, University of Sydney, Camperdown, Australia 6 2 Clinical Pharmacology & Toxicology, SydPath, St Vincent’s Hospital, Darlinghurst, 7 Australia 8 3 Centre for Infectious Diseases & Microbiol...
متن کاملSuccessful management of voriconazole-associated hyponatremia with therapeutic drug monitoring.
Voriconazole is a broad-spectrum triazole antifungal agent and the first-choice therapy for invasive aspergillosis (IA) (1). Although voriconazole is generally well tolerated, anecdotal case reports have described unexpected severe adverse events related to voriconazole, such as hyponatremia, which potentially could result in death (2–4). We report a case of successful voriconazole treatment of...
متن کاملA Review on Therapeutic Drug Monitoring of Immunosuppressant Drugs
Immunosuppressants require therapeutic drug monitoring because of their narrow therapeutic index and significant inter-individual variability in blood concentrations. This variability can be because of factors like drug-nutrient interactions, drug-disease interactions, renal-insufficiency, inflammation and infection, gender, age, polymorphism and liver mass. Drug monitoring is widely practiced ...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2016
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkw099